| Data | In casa | Ospite | Risultato |
|---|---|---|---|
| 12/09/25 20.30 | UD Las Palmas | Real Sociedad B | 2:1 |
| 13/09/25 16.15 | CD Mirandes | Deportivo La Coruna | 1:5 |
| 13/09/25 16.15 | FC Cadiz | SD Eibar | 1:0 |
| 13/09/25 18.30 | SD Huesca | FC Malaga | 1:0 |
| 13/09/25 21.00 | Real Valladolid | UD Almeria | 3:1 |
| 14/09/25 14.00 | Andorra CF | Cordoba CF | 3:1 |
| 14/09/25 16.15 | Racing Santander | CyD Leonesa | 2:4 |
| 14/09/25 18.30 | Sporting Gijon | Burgos CF | 2:3 |
| 14/09/25 18.30 | CD Castellon | AD Ceuta FC | 3:3 |
| 14/09/25 21.00 | FC Granada | CD Leganes | 0:2 |
| 15/09/25 20.30 | Real Saragossa | Albacete Balompie | 0:0 |