| Data | In casa | Ospite | Risultato |
|---|---|---|---|
| 24/11/22 18.30 | Detroit Lions | Buffalo Bills | 25:28 |
| 24/11/22 22.30 | Dallas Cowboys | New York Giants | 28:20 |
| 25/11/22 02.20 | Minnesota Vikings | New England Patriots | 33:26 |
| 27/11/22 19.00 | New York Jets | Chicago Bears | 31:10 |
| 27/11/22 19.00 | Washington Commanders | Atlanta Falcons | 19:13 |
| 27/11/22 19.00 | Carolina Panthers | Denver Broncos | 23:10 |
| 27/11/22 19.00 | Jacksonville Jaguars | Baltimore Ravens | 28:27 |
| 27/11/22 19.00 | Miami Dolphins | Houston Texans | 30:15 |
| 27/11/22 19.00 | Cleveland Browns | Tampa Bay Buccaneers | 23:17OT |
| 27/11/22 19.00 | Tennessee Titans | Cincinnati Bengals | 16:20 |
| 27/11/22 22.05 | Seattle Seahawks | Las Vegas Raiders | 34:40OT |
| 27/11/22 22.05 | Arizona Cardinals | Los Angeles Chargers | 24:25 |
| 27/11/22 22.25 | Kansas City Chiefs | Los Angeles Rams | 26:10 |
| 27/11/22 22.25 | San Francisco 49ers | New Orleans Saints | 13:0 |
| 28/11/22 02.20 | Philadelphia Eagles | Green Bay Packers | 40:33 |
| 29/11/22 02.15 | Indianapolis Colts | Pittsburgh Steelers | 17:24 |