| Eastern Conference | Prt | Punti | Reti | Diff | v | p | s | |
|---|---|---|---|---|---|---|---|---|
| 1. | Cincinnati FC | 17 | 41 | 33:13 | 20 | 13 | 2 | 2 |
| 2. | Columbus Crew | 17 | 40 | 41:14 | 27 | 12 | 4 | 1 |
| 3. | New England Revolution | 17 | 40 | 37:16 | 21 | 12 | 4 | 1 |
| 4. | Philadelphia Union | 17 | 36 | 33:13 | 20 | 10 | 6 | 1 |
| 5. | Atlanta United FC | 17 | 34 | 42:21 | 21 | 10 | 4 | 3 |
| 6. | CF Montreal | 17 | 33 | 26:12 | 14 | 10 | 3 | 4 |
| 7. | Orlando City | 17 | 32 | 31:19 | 12 | 9 | 5 | 3 |
| 8. | Nashville SC | 17 | 31 | 25:13 | 12 | 9 | 4 | 4 |
| 9. | New York City FC | 17 | 30 | 23:16 | 7 | 8 | 6 | 3 |
| 10. | New York Red Bulls | 17 | 26 | 21:17 | 4 | 7 | 5 | 5 |
| 11. | Charlotte FC | 17 | 26 | 24:21 | 3 | 6 | 8 | 3 |
| 12. | Chicago Fire | 17 | 25 | 26:22 | 4 | 6 | 7 | 4 |
| 13. | D.C. United | 17 | 24 | 31:23 | 8 | 6 | 6 | 5 |
| 14. | Inter Miami CF | 17 | 23 | 25:21 | 4 | 6 | 5 | 6 |
| 15. | Toronto FC | 17 | 18 | 19:22 | -3 | 4 | 6 | 7 |
| Western Conference | Prt | Punti | Reti | Diff | v | p | s | |
|---|---|---|---|---|---|---|---|---|
| 1. | Houston Dynamo | 17 | 37 | 36:11 | 25 | 11 | 4 | 2 |
| 2. | St. Louis City SC | 17 | 35 | 41:17 | 24 | 11 | 2 | 4 |
| 3. | Los Angeles FC | 17 | 33 | 36:17 | 19 | 10 | 3 | 4 |
| 4. | San Jose Earthquakes | 17 | 31 | 25:16 | 9 | 8 | 7 | 2 |
| 5. | Vancouver Whitecaps | 17 | 30 | 35:19 | 16 | 8 | 6 | 3 |
| 6. | Portland Timbers | 17 | 30 | 29:22 | 7 | 9 | 3 | 5 |
| 7. | Sporting Kansas City | 17 | 29 | 30:21 | 9 | 9 | 2 | 6 |
| 8. | FC Dallas | 17 | 28 | 23:16 | 7 | 7 | 7 | 3 |
| 9. | Seattle Sounders | 17 | 27 | 19:11 | 8 | 7 | 6 | 4 |
| 10. | Austin FC | 17 | 25 | 28:22 | 6 | 7 | 4 | 6 |
| 11. | Los Angeles Galaxy | 17 | 24 | 31:29 | 2 | 6 | 6 | 5 |
| 12. | Real Salt Lake | 17 | 22 | 25:27 | -2 | 6 | 4 | 7 |
| 13. | Minnesota United FC | 17 | 21 | 24:20 | 4 | 4 | 9 | 4 |
| 14. | Colorado Rapids | 17 | 17 | 13:16 | -3 | 3 | 8 | 6 |