| Eastern Conference | Prt | Punti | Reti | Diff | v | p | s | |
|---|---|---|---|---|---|---|---|---|
| 1. | Nashville SC | 28 | 63 | 59:22 | 37 | 19 | 6 | 3 |
| 2. | Inter Miami CF | 28 | 49 | 68:50 | 18 | 13 | 10 | 5 |
| 3. | Chicago Fire | 28 | 48 | 51:40 | 11 | 14 | 6 | 8 |
| 4. | Charlotte FC | 28 | 46 | 50:40 | 10 | 13 | 7 | 8 |
| 5. | New England Revolution | 28 | 46 | 45:39 | 6 | 14 | 4 | 10 |
| 6. | Philadelphia Union | 28 | 42 | 56:45 | 11 | 12 | 6 | 10 |
| 7. | Orlando City | 28 | 37 | 51:66 | -15 | 11 | 4 | 13 |
| 8. | Cincinnati FC | 27 | 36 | 58:65 | -7 | 9 | 9 | 9 |
| 9. | New York Red Bulls | 28 | 36 | 38:52 | -14 | 10 | 6 | 12 |
| 10. | New York City FC | 28 | 33 | 42:38 | 4 | 8 | 9 | 11 |
| 11. | Toronto FC | 28 | 32 | 41:52 | -11 | 7 | 11 | 10 |
| 12. | D.C. United | 27 | 30 | 34:46 | -12 | 6 | 12 | 9 |
| 13. | Columbus Crew | 28 | 29 | 41:46 | -5 | 8 | 5 | 15 |
| 14. | Atlanta United FC | 28 | 27 | 33:48 | -15 | 7 | 6 | 15 |
| 15. | CF Montreal | 28 | 24 | 35:56 | -21 | 6 | 6 | 16 |
| Western Conference | Prt | Punti | Reti | Diff | v | p | s | |
|---|---|---|---|---|---|---|---|---|
| 1. | Vancouver Whitecaps | 28 | 51 | 61:30 | 31 | 15 | 6 | 7 |
| 2. | St. Louis City SC | 28 | 50 | 54:38 | 16 | 14 | 8 | 6 |
| 3. | FC Dallas | 28 | 47 | 52:45 | 7 | 13 | 8 | 7 |
| 4. | San Jose Earthquakes | 28 | 46 | 50:40 | 10 | 13 | 7 | 8 |
| 5. | Houston Dynamo | 28 | 45 | 36:34 | 2 | 13 | 6 | 9 |
| 6. | Los Angeles FC | 29 | 42 | 44:31 | 13 | 11 | 9 | 9 |
| 7. | Seattle Sounders | 28 | 41 | 38:35 | 3 | 11 | 8 | 9 |
| 8. | Colorado Rapids | 28 | 37 | 39:39 | 0 | 11 | 4 | 13 |
| 9. | Los Angeles Galaxy | 29 | 36 | 39:50 | -11 | 9 | 9 | 11 |
| 10. | Portland Timbers | 28 | 33 | 51:54 | -3 | 9 | 6 | 13 |
| 11. | San Diego FC | 28 | 32 | 48:51 | -3 | 8 | 8 | 12 |
| 12. | Real Salt Lake | 28 | 32 | 41:46 | -5 | 9 | 5 | 14 |
| 13. | Austin FC | 28 | 31 | 36:51 | -15 | 7 | 10 | 11 |
| 14. | Minnesota United FC | 28 | 30 | 42:51 | -9 | 7 | 9 | 12 |
| 15. | Sporting Kansas City | 28 | 22 | 35:68 | -33 | 6 | 4 | 18 |