| Data | In casa | Ospite | Risultato |
|---|---|---|---|
| 20/10/24 00.00 | Orlando City | Atlanta United FC | -:- |
| 20/10/24 00.00 | Inter Miami CF | New England Revolution | -:- |
| 20/10/24 00.00 | Chicago Fire | Nashville SC | -:- |
| 20/10/24 00.00 | Philadelphia Union | Cincinnati FC | -:- |
| 20/10/24 00.00 | New York Red Bulls | Columbus Crew | -:- |
| 20/10/24 00.00 | D.C. United | Charlotte FC | -:- |
| 20/10/24 00.00 | CF Montreal | New York City FC | -:- |
| 20/10/24 03.00 | Seattle Sounders | Portland Timbers | -:- |
| 20/10/24 03.00 | Austin FC | Colorado Rapids | -:- |
| 20/10/24 03.00 | Real Salt Lake | Vancouver Whitecaps | -:- |
| 20/10/24 03.00 | Houston Dynamo | Los Angeles Galaxy | -:- |
| 20/10/24 03.00 | Los Angeles FC | San Jose Earthquakes | -:- |
| 20/10/24 03.00 | Minnesota United FC | St. Louis City SC | -:- |
| 20/10/24 03.00 | FC Dallas | Sporting Kansas City | -:- |