| Data | In casa | Ospite | Risultato |
|---|---|---|---|
| 02/04/23 01.30 | Philadelphia Union | Sporting Kansas City | 0:0 |
| 02/04/23 01.30 | New England Revolution | New York City FC | 1:1 |
| 02/04/23 01.30 | Orlando City | Nashville SC | 0:2 |
| 02/04/23 01.30 | Columbus Crew | Real Salt Lake | 4:0 |
| 02/04/23 01.30 | Los Angeles Galaxy | Seattle Sounders | 1:2 |
| 02/04/23 01.30 | Atlanta United FC | New York Red Bulls | 1:0 |
| 02/04/23 01.30 | Cincinnati FC | Inter Miami CF | 1:0 |
| 02/04/23 01.30 | Toronto FC | Charlotte FC | 2:2 |
| 02/04/23 02.30 | FC Dallas | Portland Timbers | 1:1 |
| 02/04/23 02.30 | Chicago Fire | D.C. United | 0:0 |
| 02/04/23 02.30 | St. Louis City SC | Minnesota United FC | 0:1 |
| 02/04/23 03.30 | Colorado Rapids | Los Angeles FC | 0:0 |
| 02/04/23 04.30 | Vancouver Whitecaps | CF Montreal | 5:0 |
| 02/04/23 04.30 | San Jose Earthquakes | Houston Dynamo | 2:1 |