| Data | In casa | Ospite | Risultato |
|---|---|---|---|
| 18/03/23 21.00 | Seattle Sounders | Los Angeles FC | 0:0 |
| 19/03/23 00.30 | Toronto FC | Inter Miami CF | 2:0 |
| 19/03/23 00.30 | CF Montreal | Philadelphia Union | 3:2 |
| 19/03/23 00.30 | Atlanta United FC | Portland Timbers | 5:1 |
| 19/03/23 00.30 | New York Red Bulls | Columbus Crew | 2:1 |
| 19/03/23 00.30 | New England Revolution | Nashville SC | 1:0 |
| 19/03/23 00.30 | Orlando City | Charlotte FC | 1:2 |
| 19/03/23 00.30 | New York City FC | D.C. United | 3:2 |
| 19/03/23 01.30 | St. Louis City SC | San Jose Earthquakes | 3:0 |
| 19/03/23 01.30 | FC Dallas | Sporting Kansas City | 2:1 |
| 19/03/23 01.30 | Houston Dynamo | Austin FC | 2:0 |
| 19/03/23 01.30 | Chicago Fire | Cincinnati FC | 3:3 |
| 19/03/23 02.30 | Colorado Rapids | Minnesota United FC | 1:2 |
| 19/03/23 03.30 | Los Angeles Galaxy | Vancouver Whitecaps | 1:1 |