| Data | In casa | Ospite | Risultato |
|---|---|---|---|
| 18/05/23 01.30 | Cincinnati FC | CF Montreal | 3:0 |
| 18/05/23 01.30 | Toronto FC | New York Red Bulls | 0:0 |
| 18/05/23 01.30 | Orlando City | New York City FC | 1:1 |
| 18/05/23 01.30 | Philadelphia Union | D.C. United | 0:0 |
| 18/05/23 01.30 | Charlotte FC | Chicago Fire | 2:1 |
| 18/05/23 01.30 | Columbus Crew | Los Angeles Galaxy | 2:0 |
| 18/05/23 01.30 | Atlanta United FC | Colorado Rapids | 4:0 |
| 18/05/23 02.30 | FC Dallas | Vancouver Whitecaps | 2:1 |
| 18/05/23 02.30 | Minnesota United FC | Houston Dynamo | 1:0 |
| 18/05/23 02.30 | Nashville SC | Inter Miami CF | 2:1 |
| 18/05/23 03.30 | Real Salt Lake | Portland Timbers | 0:0 |
| 18/05/23 04.30 | Seattle Sounders | Austin FC | 1:2 |
| 18/05/23 04.30 | Los Angeles FC | Sporting Kansas City | 1:1 |