| Data | In casa | Ospite | Risultato |
|---|---|---|---|
| 31/08/25 01.30 | New York Red Bulls | Columbus Crew | -:- |
| 31/08/25 01.30 | Cincinnati FC | Philadelphia Union | -:- |
| 31/08/25 01.30 | New England Revolution | Charlotte FC | -:- |
| 31/08/25 01.30 | Toronto FC | CF Montreal | -:- |
| 31/08/25 01.30 | New York City FC | D.C. United | -:- |
| 31/08/25 02.30 | St. Louis City SC | Houston Dynamo | -:- |
| 31/08/25 02.30 | Sporting Kansas City | Colorado Rapids | -:- |
| 31/08/25 02.30 | Nashville SC | Atlanta United FC | -:- |
| 31/08/25 02.30 | Austin FC | San Jose Earthquakes | -:- |
| 31/08/25 02.30 | Minnesota United FC | Portland Timbers | -:- |
| 01/09/25 04.45 | Los Angeles FC | San Diego FC | -:- |
| 01/10/25 01.30 | Inter Miami CF | Chicago Fire | -:- |
| 12/10/25 01.30 | Orlando City | Vancouver Whitecaps | -:- |
| 12/10/25 03.30 | Seattle Sounders | Real Salt Lake | -:- |
| 12/10/25 04.30 | Los Angeles Galaxy | FC Dallas | -:- |