| Data | In casa | Ospite | Risultato |
|---|---|---|---|
| 25/04/26 19.00 | Toronto FC | Atlanta United FC | 1:2 |
| 25/04/26 20.30 | CF Montreal | New York City FC | 1:0 |
| 25/04/26 22.45 | Minnesota United FC | Los Angeles FC | 0:1 |
| 26/04/26 01.30 | Cincinnati FC | New York Red Bulls | 2:0 |
| 26/04/26 01.30 | Inter Miami CF | New England Revolution | 1:1 |
| 26/04/26 01.30 | Columbus Crew | Philadelphia Union | 2:0 |
| 26/04/26 01.30 | D.C. United | Orlando City | 3:2 |
| 26/04/26 02.30 | Chicago Fire | Sporting Kansas City | 5:0 |
| 26/04/26 02.30 | Austin FC | Houston Dynamo | 2:0 |
| 26/04/26 02.40 | Nashville SC | Charlotte FC | 4:2 |
| 26/04/26 02.40 | St. Louis City SC | San Jose Earthquakes | 2:3 |
| 26/04/26 03.40 | San Diego FC | Portland Timbers | 1:2 |
| 26/04/26 04.30 | Vancouver Whitecaps | Colorado Rapids | 3:1 |
| 26/04/26 04.30 | Seattle Sounders | FC Dallas | 2:1 |
| 27/04/26 01.00 | Los Angeles Galaxy | Real Salt Lake | 2:1 |