| Data | In casa | Ospite | Risultato |
|---|---|---|---|
| 26/11/22 13.45 | Kings Lynn FC | Stevenage FC | 0:3 |
| 26/11/22 16.00 | Forest Green Rovers | Alvechurch | 2:1 |
| 26/11/22 16.00 | Sheffield Wednesday | Mansfield Town | 2:1 |
| 26/11/22 16.00 | FC Walsall | Carlisle United | 2:1 |
| 26/11/22 16.00 | FC Portsmouth | Milton Keynes Dons FC | 3:2 |
| 26/11/22 16.00 | FC Barnsley | Crewe Alexandra | 3:0 |
| 26/11/22 16.00 | Charlton Athletic | Stockport County | 2:2 |
| 26/11/22 16.00 | Accrington Stanley | FC Barnet | 1:0 |
| 26/11/22 16.00 | Hartlepool United | Harrogate Town FC | 3:1 |
| 26/11/22 16.00 | AFC Wimbledon | FC Chesterfield | 0:2 |
| 26/11/22 16.00 | Cambridge United | Grimsby Town | 1:2 |
| 26/11/22 16.00 | Oxford United | Exeter City | 4:1 |
| 26/11/22 16.00 | Shrewsbury Town | Peterborough United | 3:1 |
| 26/11/22 16.15 | AFC Wrexham | Farnborough | 4:1 |
| 26/11/22 18.00 | Dagenham and Redbridge | FC Gillingham | 1:1 |
| 27/11/22 13.30 | Ebbsfleet United | Fleetwood Town | 0:1 |
| 27/11/22 15.00 | Bristol Rovers | Boreham Wood | 0:2 |
| 27/11/22 15.00 | Burton Albion | Chippenham Town | 6:1 |
| 27/11/22 16.15 | Newport County | Derby County | 1:2 |
| 27/11/22 18.00 | Ipswich Town | Buxton FC | 4:0 |
| 07/12/22 20.45 | Stockport County | Charlton Athletic | 3:1 |
| 08/12/22 20.15 | FC Gillingham | Dagenham and Redbridge | 3:2 |