| Data | In casa | Ospite | Risultato |
|---|---|---|---|
| 27/11/24 16.30 | Istanbul Basaksehir FK | FC Petrocub Hincesti | 1:1 |
| 28/11/24 16.30 | FK Astana | Vitoria Guimaraes | 1:1 |
| 28/11/24 18.45 | Dinamo Minsk | FC Copenhagen | 1:2 |
| 28/11/24 18.45 | 1. FC Heidenheim 1846 | FC Chelsea | 0:2 |
| 28/11/24 18.45 | Molde FK | APOEL Nicosia | 0:1 |
| 28/11/24 18.45 | KSV Cercle Brügge | Heart of Midlothian | 2:0 |
| 28/11/24 18.45 | The New Saints FC | Djurgardens IF | 0:1 |
| 28/11/24 18.45 | Panathinaikos Atene | HJK Helsinki | 1:0 |
| 28/11/24 18.45 | FK Borac | Linzer ASK | 2:1 |
| 28/11/24 18.45 | FC St.Gallen | TSC Backa Topola | 2:2 |
| 28/11/24 18.45 | NK Celje | Jagiellonia Bialystok | 3:3 |
| 28/11/24 18.45 | FC Noah | Vikingur Reykjavik | 0:0 |
| 28/11/24 21.00 | FC Lugano | KAA Gent | 2:0 |
| 28/11/24 21.00 | Olimpija Ljubljana | Larne FC | 1:0 |
| 28/11/24 21.00 | Omonia Nicosia | Legia Varsavia | 0:3 |
| 28/11/24 21.00 | SK Rapid Vienna | Shamrock Rovers | 1:1 |
| 28/11/24 21.00 | FK Mlada Boleslav | Real Betis Siviglia | 2:1 |
| 28/11/24 21.00 | Fiorentina | Pafos FC | 3:2 |