Calendario partite
| Data | Termine inser. pron. | In casa | Ospite | Risultato | Regola punti |
|---|---|---|---|---|---|
| 15/10/21 20.30 | 15/10/21 20.30 | 1899 Hoffenheim | 1. FC Colonia | 5:0 | 4 - 4 - 4 |
| 16/10/21 15.30 | 16/10/21 15.30 | 1. FC Union Berlino | VfL Wolfsburg | 2:0 | 4 - 4 - 5 |
| 16/10/21 15.30 | 16/10/21 15.30 | Eintracht Francoforte | Hertha BSC | 1:2 | 2 - 10 - 10 |
| 16/10/21 15.30 | 16/10/21 15.30 | Borussia Dortmund | FSV Magonza 05 | 3:1 | 2 - 10 - 10 |
| 16/10/21 15.30 | 16/10/21 15.30 | SpVgg Greuther Fürth | VfL Bochum | 0:1 | 4 - 5 - 3 |
| 16/10/21 15.30 | 16/10/21 15.30 | SC Friburgo | RB Lipsia | 1:1 | 5 - 4 - 3 |
| 16/10/21 18.30 | 16/10/21 18.30 | Bor. Mönchengladbach | VfB Stoccarda | 1:1 | 2 - 10 - 7 |
| 17/10/21 15.30 | 17/10/21 15.30 | Bayer 04 Leverkusen | FC Bayern Monaco | 1:5 | 9 - 7 - 2 |
| 17/10/21 17.30 | 17/10/21 17.30 | FC Augusta | Arminia Bielefeld | 1:1 | 3 - 5 - 6 |