Calendario partite
| Data | Termine inser. pron. | In casa | Ospite | Risultato | Regola punti |
|---|---|---|---|---|---|
| 01/10/21 20.30 | 01/10/21 20.30 | 1. FC Colonia | SpVgg Greuther Fürth | 3:1 | 2 - 7 - 8 |
| 02/10/21 15.30 | 02/10/21 15.30 | Hertha BSC | SC Friburgo | 1:2 | 4 - 4 - 3 |
| 02/10/21 15.30 | 02/10/21 15.30 | VfB Stoccarda | 1899 Hoffenheim | 3:1 | 5 - 3 - 3 |
| 02/10/21 15.30 | 02/10/21 15.30 | VfL Wolfsburg | Bor. Mönchengladbach | 1:3 | 3 - 4 - 5 |
| 02/10/21 15.30 | 02/10/21 15.30 | Borussia Dortmund | FC Augusta | 2:1 | 2 - 8 - 8 |
| 02/10/21 18.30 | 02/10/21 18.30 | RB Lipsia | VfL Bochum | 3:0 | 2 - 8 - 8 |
| 03/10/21 15.30 | 03/10/21 15.30 | FSV Magonza 05 | 1. FC Union Berlino | 1:2 | 3 - 3 - 6 |
| 03/10/21 17.30 | 03/10/21 17.30 | FC Bayern Monaco | Eintracht Francoforte | 1:2 | 2 - 8 - 8 |
| 03/10/21 19.30 | 03/10/21 19.30 | Arminia Bielefeld | Bayer 04 Leverkusen | 0:4 | 8 - 8 - 2 |