Calendario partite
| Data | Termine inser. pron. | In casa | Ospite | Risultato | Regola punti |
|---|---|---|---|---|---|
| 11/09/21 15.30 | 11/09/21 15.30 | SpVgg Greuther Fürth | VfL Wolfsburg | 0:2 | 8 - 8 - 2 |
| 11/09/21 15.30 | 11/09/21 15.30 | 1899 Hoffenheim | FSV Magonza 05 | 0:2 | 2 - 5 - 6 |
| 11/09/21 15.30 | 11/09/21 15.30 | SC Friburgo | 1. FC Colonia | 1:1 | 3 - 5 - 5 |
| 11/09/21 15.30 | 11/09/21 15.30 | 1. FC Union Berlino | FC Augusta | 0:0 | 2 - 6 - 8 |
| 11/09/21 15.30 | 11/09/21 15.30 | Bayer 04 Leverkusen | Borussia Dortmund | 3:4 | 4 - 4 - 3 |
| 11/09/21 18.30 | 11/09/21 18.30 | RB Lipsia | FC Bayern Monaco | 1:4 | 6 - 6 - 2 |
| 12/09/21 15.30 | 12/09/21 15.30 | Eintracht Francoforte | VfB Stoccarda | 1:1 | 3 - 4 - 6 |
| 12/09/21 17.30 | 12/09/21 17.30 | VfL Bochum | Hertha BSC | 1:3 | 4 - 4 - 4 |
| 12/09/21 19.30 | 12/09/21 19.30 | Bor. Mönchengladbach | Arminia Bielefeld | 3:1 | 2 - 8 - 8 |